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ONC0252A Basic histology and human embryology

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Basic histology and human embryology

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Academic year 2023/2024

Course ID
ONC0252A
Teachers
Sabrina Arena (Lecturer)
Silvia Giordano (Lecturer)
Year
1st year
Teaching period
First semester
Type
Basic
Credits/Recognition
2
Course disciplinary sector (SSD)
BIO/17 - histology
Delivery
Formal authority
Language
English
Attendance
Obligatory
Type of examination
Written and oral
Type of learning unit
modulo
Modular course
Tissue pathophysiology and genetics (ONC0252)
Prerequisites
Students will need to have a basic knowledge of physics, chemistry, biochemistry, cellular biology and genetics.
Propedeutic for
Anatomy
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Sommario del corso

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Course objectives

The main objective of the course is offering basic knowledge of classical histology with functional links to cell morphology and tissues. At the end of the course the student should know the methods and morphological survey tools about the morphology of the cells and tissues of the human organism.

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Results of learning outcomes

KNOWLEDGE AND UNDERSTANDING

At the end of the course, students should be able to recognize the various types of tissues and the main cellular subtypes, structures and specializations of the tissues (epithelia, connective tissue, cartilage, bone, adipose tissue, blood, nervous and muscle tissues, basic notions of embryology). They will also have to know the main instruments, staining and analysis techniques for tissue studies.

ABILITY TO APPLY KNOWLEDGE AND UNDERSTANDING

The students will have to demonstrate:

- to have acquired basic knowledge of the main instruments to observe histological samples (optical, electronic and fluorescent microscopes) and of the most common types of histological stainings and tissue analysis techniques (immunohistochemistry, immunofluorescence);

- to be able to correlate the morphological characteristics and functional specializations of the main cellular subtypes of the tissue they belong to.

 

AUTONOMY OF JUDGMENT

The students should be able to identify and critically interpret the information necessary to understand the structure, organization and function of cells and tissues.

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Program

  1. Introduction to cell morphology and related functions. The histological techniques.
  2. Epithelia I: classification (surface, glandular and sensory), morphology and functional aspects.
  3. Epithelia II: classification (surface, glandular and sensory), morphology and functional aspects.
  4. Sensory epithelia
  5. Nervous system: classification, morphology and functional aspects.
  6. Connective tissue: classification (proper, adipose, cartilage, bone and blood tissues), morphology and functional aspects.
  7. Cartilage and bone: classification, morphology and functional aspects.
  8. Structure and function of the smooth, striated and cardiac muscle tissue.
  9. Morphofunctional aspects of plasma and blood. Liquid biopsy.
  10. Hints on haematopoiesis and immune system.
  11. Notions of embryology I (from gametogenesis to the first week of embryonic development)
  12. Notions of embryology II (from the second to the fourth week of embryonic development)
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Course delivery

The course will take place in 24 hours of frontal lessons. Specific iconography (power point slides) will be projected to support the theoretical foundations.

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Learning assessment methods

The final test is a written exam, constituted by 30 quiz questions.
The questions will be aimed to ascertain the student knowledge on the topics defined in the course program.

An oral examination might follow to improve the score.

The result achieved in this module will be integrated with the results achieved in the other modules of the integrated course.

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Support activities

Practical lessons with microscopy use and activity will follow to support the theoretical teaching.

Suggested readings and bibliography

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  • Stevens /J. Lowe, Istologia Umana. Casa Editrice Ambrosiana
  • Wheater, Istologia e Anatomia Microscopica, Casa Editrice Ambrosiana
  • Kierzenbaum/Tres, Histology And Cell Biology: An Introduction To Pathology

 



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