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ONC0252C Organ disease pathology

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Organ disease pathology

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Academic year 2023/2024

Course ID
ONC0252C
Teacher
Marco Volante (Lecturer)
Year
1st year
Teaching period
First semester
Type
Basic
Credits/Recognition
1
Course disciplinary sector (SSD)
MED/08 - pathology
Delivery
Formal authority
Language
English
Attendance
Obligatory
Type of examination
Written and oral
Type of learning unit
modulo
Modular course
Tissue pathophysiology and genetics (ONC0252)
Propedeutic for
The module in the same course of Imaging techniques in physio-pathology and comparative microscopy (ONC0252D)
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Sommario del corso

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Course objectives

Aim of the present module is to describe the cellular and architectural morphological changes that in organ-specific settings lead to the identification of specific diseases and to the recognition of morphological parameters associated with a given biological and/or clinical behavior. The integration of morphology with ancillary methods (such as immunohistochemistry and in situ molecular techniques) in the process of characterization of organ-specific diseases will be also discussed

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Results of learning outcomes

At the end of the course, students should be able to:

- recognize the value of various morphological parameters in the definition of diagnosis, prognosis and prediction of response to therapy in different organ/system settings

- identify the heterogeneous cell components populating inflammatory and tumor lesions in different organ/system settings

- critically interpret images of both conventional morphological stainings and in situ ancillary techniques

- know the main current applications of artificial intelligence in pathology

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Program

Principles of macroscopic analysis (including imaging of specimens) and sampling

Principles of cytological vs histological samples diagnostic approaches

Inflammatory diseases in different organs/systems

Principles of organ-specific classifications of tumors

Principles of staging of tumors (with special reference to morphology-based quantification issues)

Principles of intra-lesional cellular heterogeneity (with special reference to tumors)

Application of ancillary tools in organ-specific disease settings

Principles of application of artificial intelligence in the identification and characterization of diseases

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Course delivery

Lectures with slides, discussion of review articles, summary tables and representative images for each different setting

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Learning assessment methods

Questions to students during lectures. Written test with multiple choice questions and oral discussion at the end of the course

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Support activities

Slides of each lecture in PDF format. Summary atlas of all images discussed in the course.

Practical activity with the microscope using digitalized slides and image quantification tools.

Suggested readings and bibliography

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Robbins and Cotran -; Pathology Basis of Disease Elsevier 2021

Free-access website of pathology description and imaging (PathologyOutlines.com, Inc. at https://www.pathologyoutlines.com/)



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